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Target
Delta-type opioid receptor
Ligand
BDBM50067446
Substrate
n/a
Meas. Tech.
ChEMBL_147279 (CHEMBL755201)
Ki
750±n/a nM
Citation
 Thomas, JB; Zheng, X; Mascarella, SW; Rothman, RB; Dersch, CM; Partilla, JS; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI N-Substituted 9beta-methyl-5-(3-hydroxyphenyl)morphans are opioid receptor pure antagonists. J Med Chem 41:4143-9 (1998) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50067446
Synonyms:
3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol | CHEMBL133815
Type:
Small organic molecule
Emp. Form.:
C16H23NO
Mol. Mass.:
245.3599
SMILES:
C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1
Structure:
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