Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50513557
Substrate
n/a
Meas. Tech.
ChEMBL_1853611 (CHEMBL4354235)
Ki
5.1±n/a nM
Citation
 Zhang, M; Fan, S; Zhou, X; Xie, F; Li, S; Zhong, W Design, synthesis and biological evaluation of 2-hydrazinyladenosine derivatives as A Eur J Med Chem 179:310-324 (2019) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50513557
Synonyms:
CHEMBL4439605
Type:
Small organic molecule
Emp. Form.:
C21H26N8O4
Mol. Mass.:
454.4823
SMILES:
Nc1nc(N\N=C\c2ccc(cc2)N2CCCC2)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Structure:
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