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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50068929
Substrate
n/a
Meas. Tech.
ChEBML_79947
IC50
41±n/a nM
Citation
 Patel, NM; Bennett, F; Girijavallabhan, VM; Dasmahapatra, B; Butkiewicz, N; Hart, A Novel HIV-protease inhibitors containing beta-hydroxyether and -thioether dipeptide isostere surrogates: modification of the P3 ligand. Bioorg Med Chem Lett 8:931-4 (1999) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50068929
Synonyms:
(S)-N*1*-[(1S,2S)-1-Benzyl-3-(2-tert-butylcarbamoyl-phenoxy)-2-hydroxy-propyl]-2-[(9,10-dioxo-9,10-dihydro-anthracene-2-carbonyl)-amino]-succinamide | CHEMBL175214
Type:
Small organic molecule
Emp. Form.:
C40H40N4O8
Mol. Mass.:
704.7676
SMILES:
CC(C)(C)NC(=O)c1ccccc1OC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2C(=O)c3ccccc3C(=O)c2c1
Structure:
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