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Target
D(2) dopamine receptor
Ligand
BDBM50069011
Substrate
n/a
Meas. Tech.
ChEBML_62390
Ki
31±n/a nM
Citation
 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP Azepinoindole derivatives with high affinity for brain dopamine and serotonin receptors. Bioorg Med Chem Lett 8:983-8 (1999) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50069011
Synonyms:
1-(4-Fluoro-phenyl)-8,9-dimethoxy-4-methyl-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole | CHEMBL178797
Type:
Small organic molecule
Emp. Form.:
C20H23FN2O2
Mol. Mass.:
342.4072
SMILES:
COc1cc2CCN(C)CC3CN(c(c23)c1OC)c1ccc(F)cc1
Structure:
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