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Target
Lactoylglutathione lyase
Ligand
BDBM50069024
Substrate
n/a
Meas. Tech.
ChEMBL_71305 (CHEMBL686108)
Ki
1900±n/a nM
Citation
 Ly, HD; Clugston, SL; Sampson, PB; Honek, JF Syntheses and kinetic evaluation of hydroxamate-based peptide inhibitors of glyoxalase I. Bioorg Med Chem Lett 8:705-10 (1999) [PubMed]  Article 
Target
Name:
Lactoylglutathione lyase
Synonyms:
Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase
Type:
Enzyme
Mol. Mass.:
20772.95
Organism:
Homo sapiens (Human)
Description:
Q04760
Residue:
184
Sequence:
MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM
  
Inhibitor
Name:
BDBM50069024
Synonyms:
2-Amino-4-[1-(carboxymethyl-carbamoyl)-3-(hydroxy-methyl-carbamoyl)-propylcarbamoyl]-butyric acid anion | CHEMBL159603
Type:
Small organic molecule
Emp. Form.:
C13H22N4O8
Mol. Mass.:
362.3358
SMILES:
CN(O)C(=O)CCC(NC(=O)CCC([NH3+])C([O-])=O)C(=O)NCC(O)=O
Structure:
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