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Target
Cytochrome c oxidase subunit 1
Ligand
BDBM50513906
Substrate
n/a
Meas. Tech.
ChEMBL_1854910 (CHEMBL4355639)
IC50
6000±n/a nM
Citation
 Sangshetti, J; Pathan, SK; Patil, R; Akber Ansari, S; Chhajed, S; Arote, R; Shinde, DB Synthesis and biological activity of structurally diverse phthalazine derivatives: A systematic review. Bioorg Med Chem 27:3979-3997 (2019) [PubMed]  Article 
Target
Name:
Cytochrome c oxidase subunit 1
Synonyms:
COI | COX1_SHEEP | COXI | MT-CO1 | MTCO1
Type:
PROTEIN
Mol. Mass.:
57042.19
Organism:
Ovis aries
Description:
ChEMBL_662814
Residue:
514
Sequence:
MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMIFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
  
Inhibitor
Name:
BDBM50513906
Synonyms:
CHEMBL4549769
Type:
Small organic molecule
Emp. Form.:
C22H19N3O3S
Mol. Mass.:
405.47
SMILES:
Cc1ccc(cc1C)-c1nn(-c2ccc(cc2)S(N)(=O)=O)c(=O)c2ccccc12
Structure:
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