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Target
Bromodomain-containing protein 9
Ligand
BDBM50266968
Substrate
n/a
Meas. Tech.
ChEMBL_1858079 (CHEMBL4358808)
Kd
82±n/a nM
Citation
 Karim, RM; Chan, A; Zhu, JY; Schönbrunn, E Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains. J Med Chem 63:3227-3237 (2020) [PubMed]  Article 
Target
Name:
Bromodomain-containing protein 9
Synonyms:
BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8
Type:
PROTEIN
Mol. Mass.:
66994.30
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108000
Residue:
597
Sequence:
MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLSSKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
  
Inhibitor
Name:
BDBM50266968
Synonyms:
CHEMBL4065619 | US11773085, Compound B27
Type:
Small organic molecule
Emp. Form.:
C20H19N3O2
Mol. Mass.:
333.3838
SMILES:
CC(=O)c1cc(-c2cc(ccc2C)C(=O)NC2CC2)c2ncccn12
Structure:
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