Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50070784
Substrate
n/a
Meas. Tech.
ChEBML_212505
Ki
153±n/a nM
Citation
 Lee, K; Hwang, SY; Yun, M; Kim, DS Potent and efficacious thienylamidine-incorporated thrombin inhibitors. Bioorg Med Chem Lett 8:1683-6 (1999) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50070784
Synonyms:
(S)-3-(5-Carbamimidoyl-thiophen-2-yl)-N-cyclopentyl-N-methyl-2-(naphthalene-2-sulfonylamino)-propionamide | CHEMBL298013
Type:
Small organic molecule
Emp. Form.:
C24H28N4O3S2
Mol. Mass.:
484.634
SMILES:
CN(C1CCCC1)C(=O)[C@H](Cc1ccc(s1)C(N)=N)NS(=O)(=O)c1ccc2ccccc2c1
Structure:
Search PDB for entries with ligand similarity: