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Target
Serine protease 1
Ligand
BDBM50071415
Substrate
n/a
Meas. Tech.
ChEBML_212510
Ki
150±n/a nM
Citation
 Buckman, BO; Mohan, R; Koovakkat, S; Liang, A; Trinh, L; Morrissey, MM Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors. Bioorg Med Chem Lett 8:2235-40 (1999) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50071415
Synonyms:
3-[9-Benzyl-6-(5-carbamimidoyl-2-hydroxy-phenoxy)-8-methyl-9H-purin-2-yloxy]-N,N-dimethyl-benzamide | CHEMBL305809
Type:
Small organic molecule
Emp. Form.:
C29H27N7O4
Mol. Mass.:
537.5692
SMILES:
CN(C)C(=O)c1cccc(Oc2nc(Oc3cc(ccc3O)C(N)=N)c3nc(C)n(Cc4ccccc4)c3n2)c1
Structure:
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