Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50516789
Substrate
n/a
Meas. Tech.
ChEMBL_1866904 (CHEMBL4367879)
Ki
2.0±n/a nM
Citation
 Ghonim, AE; Ligresti, A; Rabbito, A; Mahmoud, AM; Di Marzo, V; Osman, NA; Abadi, AH Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties. Eur J Med Chem 180:154-170 (2019) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50516789
Synonyms:
CHEMBL4559193
Type:
Small organic molecule
Emp. Form.:
C23H22N2OS
Mol. Mass.:
374.499
SMILES:
CCCCCn1c2ccccc2s\c1=N/C(=O)c1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: