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Target
Chemerin-like receptor 1
Ligand
BDBM50517138
Substrate
n/a
Meas. Tech.
ChEMBL_1867369 (CHEMBL4368344)
IC50
310±n/a nM
Citation
 Imaizumi, T; Kobayashi, A; Otsubo, S; Komai, M; Magara, M; Otsubo, N The discovery and optimization of a series of 2-aminobenzoxazole derivatives as ChemR23 inhibitors. Bioorg Med Chem 27:0 (2019) [PubMed]  Article 
Target
Name:
Chemerin-like receptor 1
Synonyms:
CML1_MOUSE | Chemokine-like receptor 1 | Cmklr1 | Dez | G-protein coupled receptor DEZ | Gpcr27
Type:
PROTEIN
Mol. Mass.:
41826.01
Organism:
Mus musculus
Description:
ChEMBL_119019
Residue:
371
Sequence:
MEYDAYNDSGIYDDEYSDGFGYFVDLEEASPWEAKVAPVFLVVIYSLVCFLGLLGNGLVIVIATFKMKKTVNTVWFVNLAVADFLFNIFLPMHITYAAMDYHWVFGKAMCKISNFLLSHNMYTSVFLLTVISFDRCISVLLPVWSQNHRSIRLAYMTCSAVWVLAFFLSSPSLVFRDTANIHGKITCFNNFSLAAPESSPHPAHSQVVSTGYSRHVAVTVTRFLCGFLIPVFIITACYLTIVFKLQRNRLAKNKKPFKIIITIIITFFLCWCPYHTLYLLELHHTAVPSSVFSLGLPLATAVAIANSCMNPILYVFMGHDFRKFKVALFSRLANALSEDTGPSSYPSHRSFTKMSSLNEKASVNEKETSTL
  
Inhibitor
Name:
BDBM50517138
Synonyms:
CHEMBL4557657
Type:
Small organic molecule
Emp. Form.:
C28H30N8O2
Mol. Mass.:
510.5902
SMILES:
CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2cc(NC(=O)NC)ccc2o1 |r|
Structure:
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