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Target
D(4) dopamine receptor
Ligand
BDBM50071858
Substrate
n/a
Meas. Tech.
ChEBML_61186
Ki
1.7±n/a nM
Citation
 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH New generation dopaminergic agents. 5. Heterocyclic bioisosteres that exploit the 3-OH-N1-phenylpiperazine dopaminergic template. Bioorg Med Chem Lett 8:2675-80 (1999) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50071858
Synonyms:
4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole | CHEMBL311539
Type:
Small organic molecule
Emp. Form.:
C19H20ClN3
Mol. Mass.:
325.835
SMILES:
Clc1ccc2[nH]ccc2c1N1CCN(Cc2ccccc2)CC1
Structure:
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