Reaction Details
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Lysophosphatidic acid receptor 1
Ligand
BDBM50517246
Substrate
n/a
Meas. Tech.
ChEMBL_1867805 (CHEMBL4368780)
IC50
5.0±n/a nM
Citation
Abdel-Magid, AF Lysophosphatidic Acid Receptor 1 Antagonists for the Treatment of Fibrosis. ACS Med Chem Lett 10:1378-1379 (2019) [PubMed] Article More Info.:
Target
Name:
Lysophosphatidic acid receptor 1
Synonyms:
EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2
Type:
Enzyme
Mol. Mass.:
41120.55
Organism:
Homo sapiens (Human)
Description:
Q92633
Residue:
364
Sequence:
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
Inhibitor
Name:
BDBM50517246
Synonyms:
CHEMBL4557434
Type:
Small organic molecule
Emp. Form.:
C25H26FN3O6
Mol. Mass.:
483.4888
SMILES:
Cc1noc(c1CNC(=O)OCc1cccc(F)c1)-c1ccc(O[C@H]2CCC[C@@H](C2)C(O)=O)cn1 |r|
Structure:
