Reaction Details Report a problem with these data
Target
Chymotrypsin-C
Ligand
BDBM50072292
Substrate
n/a
Meas. Tech.
ChEBML_49751
IC50
>100±n/a nM
Citation
 Finch, H; Pegg, NA; McLaren, J; Lowdon, A; Bolton, R; Coote, SJ; Dyer, U; Montana, JG; Owen, MR; Dowle, M; Buckley, D; Ross, BC; Campbell, C; Dix, C; Mooney, C; Man-Tang, C; Patel, C 5,5-trans lactone-containing inhibitors of serine proteases: identification of a novel, acylating thrombin inhibitor. Bioorg Med Chem Lett 8:2955-60 (1999) [PubMed]  Article 
Target
Name:
Chymotrypsin-C
Synonyms:
CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C
Type:
Enzyme
Mol. Mass.:
29487.98
Organism:
Homo sapiens (Human)
Description:
Q99895
Residue:
268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
  
Inhibitor
Name:
BDBM50072292
Synonyms:
(3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta[b]furan-2-one | CHEMBL100989
Type:
Small organic molecule
Emp. Form.:
C13H14O2S
Mol. Mass.:
234.314
SMILES:
O=C1O[C@H]2CCC[C@@H]2[C@@H]1Sc1ccccc1
Structure:
Search PDB for entries with ligand similarity: