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Target
CDGSH iron-sulfur domain-containing protein 2
Ligand
BDBM50103521
Substrate
n/a
Meas. Tech.
ChEMBL_1869768 (CHEMBL4370834)
IC50
4800±n/a nM
Citation
 Geldenhuys, WJ; Skolik, R; Konkle, ME; Menze, MA; Long, TE; Robart, AR Binding of thiazolidinediones to the endoplasmic reticulum protein nutrient-deprivation autophagy factor-1. Bioorg Med Chem Lett 29:901-904 (2019) [PubMed]  Article 
Target
Name:
CDGSH iron-sulfur domain-containing protein 2
Synonyms:
CDGSH iron-sulfur domain-containing protein 2 | CDGSH2 | CISD2 | CISD2_HUMAN | ERIS | Endoplasmic reticulum intermembrane small protein | Miner1 | MitoNEET-related 1 protein | NAF-1 | Nutrient-deprivation autophagy factor-1 | ZCD2
Type:
PROTEIN
Mol. Mass.:
15289.10
Organism:
Homo sapiens
Description:
ChEMBL_119149
Residue:
135
Sequence:
MVLESVARIVKVQLPAYLKRLPVPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV
  
Inhibitor
Name:
BDBM50103521
Synonyms:
Actos | CHEBI:8228 | Duetact | Pioglitazone | US10188639, Compound h-rac-pio | US11141411, Compound h-rac-pio
Type:
Small organic molecule
Emp. Form.:
C19H20N2O3S
Mol. Mass.:
356.439
SMILES:
CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
Structure:
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