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Target
Coagulation factor X
Ligand
BDBM50072449
Substrate
n/a
Meas. Tech.
ChEBML_226349
Ki
12±n/a nM
Citation
 Fevig, JM; Cacciola, J; Alexander, RS; Knabb, RM; Lam, GN; Wong, PC; Wexler, RR Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor Xa. Bioorg Med Chem Lett 8:3143-8 (1999) [PubMed]  Article 
Target
Name:
Coagulation factor X
Synonyms:
F10 | FA10_RABIT
Type:
PROTEIN
Mol. Mass.:
53951.21
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_1471174
Residue:
490
Sequence:
MANPLHLVLLGAALAGLLLSGSSVFISRRAANDVLARTRRANSFLEELKKGNLERECMEENCSYEEALEVFEDREKTNEFWNKYVDGDQCESNPCQNQGTCKDGLGMYTCSCVEGYEGQDCEPVTRKLCSLDNGGCDQFCKEEENSVLCSCASGYTLGDNGKSCISTELFPCGKVTLGRWRRSPATNSSEGPPEAPGPEQQDDGNLTATENPFNLLDSPEPPPEDDSSSLVRIVGGQDCRDGECPWQALLVNEENEGFCGGTILSEYHVLTAAHCLHQAKRFKVRVGDRDTEHEEGNEETHEVEVVVKHNRFVKETYDFDIAVLRLKTPITFRRNVAPACLPQKDWAESTLMAQKTGIVSGFGRTHEMGRLSTTLKMLEVPYVDRNSCKRSSSFTITQNMFCAGYDARPEDACQGDSGGPHVTRFRDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIEKSMRARAVPVAEAAGTPGPTQPTIKGSPS
  
Inhibitor
Name:
BDBM50072449
Synonyms:
CHEMBL107097 | {(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-biphenyl-4-yl)-propyl]-amino}-acetic acid; TFA
Type:
Small organic molecule
Emp. Form.:
C24H26N4O4S
Mol. Mass.:
466.553
SMILES:
NC(=N)c1cccc(c1)N(CCCc1ccc(cc1)-c1ccccc1S(N)(=O)=O)CC(O)=O
Structure:
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