Target
Coagulation factor X
Ligand
BDBM50072447
Substrate
n/a
Meas. Tech.
ChEBML_226349
Ki
51±n/a nM
Citation
 Fevig, JMCacciola, JAlexander, RSKnabb, RMLam, GNWong, PCWexler, RR Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor Xa. Bioorg Med Chem Lett 8:3143-8 (1999) [PubMed]  Article 
Target
Name:
Coagulation factor X
Synonyms:
F10 | FA10_RABIT
Type:
PROTEIN
Mol. Mass.:
53951.21
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_1471174
Residue:
490
Sequence:
MANPLHLVLLGAALAGLLLSGSSVFISRRAANDVLARTRRANSFLEELKKGNLERECMEENCSYEEALEVFEDREKTNEFWNKYVDGDQCESNPCQNQGTCKDGLGMYTCSCVEGYEGQDCEPVTRKLCSLDNGGCDQFCKEEENSVLCSCASGYTLGDNGKSCISTELFPCGKVTLGRWRRSPATNSSEGPPEAPGPEQQDDGNLTATENPFNLLDSPEPPPEDDSSSLVRIVGGQDCRDGECPWQALLVNEENEGFCGGTILSEYHVLTAAHCLHQAKRFKVRVGDRDTEHEEGNEETHEVEVVVKHNRFVKETYDFDIAVLRLKTPITFRRNVAPACLPQKDWAESTLMAQKTGIVSGFGRTHEMGRLSTTLKMLEVPYVDRNSCKRSSSFTITQNMFCAGYDARPEDACQGDSGGPHVTRFRDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIEKSMRARAVPVAEAAGTPGPTQPTIKGSPS
  
Inhibitor
Name:
BDBM50072447
Synonyms:
3-[2-(2'-Sulfamoyl-biphenyl-4-yl)-ethanesulfonylamino]-benzamidine; TFA | CHEMBL321452
Type:
Small organic molecule
Emp. Form.:
C21H22N4O4S2
Mol. Mass.:
458.554
SMILES:
NC(=N)c1cccc(NS(=O)(=O)CCc2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1
Structure:
Search PDB for entries with ligand similarity: