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Target
D(2) dopamine receptor
Ligand
BDBM50518419
Substrate
n/a
Meas. Tech.
ChEMBL_1871306 (CHEMBL4372473)
EC50
330±n/a nM
Citation
 Hall, A; Provins, L; Valade, A Novel Strategies To Activate the Dopamine D J Med Chem 62:128-140 (2019) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50518419
Synonyms:
CHEMBL4519136
Type:
Small organic molecule
Emp. Form.:
C25H28BrClN2O2
Mol. Mass.:
503.859
SMILES:
[H][C@@]12C[C@@]1(CC[C@H](C2)N1CCN(Cc2cc(Cl)ccc2Br)CC1)c1ccc2OCOc2c1 |r|
Structure:
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