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Target
D(1A) dopamine receptor
Ligand
BDBM50509151
Substrate
n/a
Meas. Tech.
ChEMBL_1871294 (CHEMBL4372461)
EC50
162±n/a nM
Citation
 Hall, A; Provins, L; Valade, A Novel Strategies To Activate the Dopamine D J Med Chem 62:128-140 (2019) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50509151
Synonyms:
CHEMBL3421730
Type:
Small organic molecule
Emp. Form.:
C22H25Cl2NO3
Mol. Mass.:
422.345
SMILES:
C[C@@H]1N([C@@H](CO)Cc2c1cccc2C(C)(C)O)C(=O)Cc1c(Cl)cccc1Cl |r|
Structure:
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