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Target
Cyclin-dependent kinase 20
Ligand
BDBM50519158
Substrate
n/a
Meas. Tech.
ChEMBL_1874021 (CHEMBL4375310)
Kd
8020±n/a nM
Citation
 Qi, B; Zhong, L; He, J; Zhang, H; Li, F; Wang, T; Zou, J; Lin, YX; Zhang, C; Guo, X; Li, R; Shi, J Discovery of Inhibitors of Aurora/PLK Targets as Anticancer Agents. J Med Chem 62:7697-7707 (2019) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 20
Synonyms:
2.7.11.22 | CAK-kinase p42 | CCRK | CDCH | CDK-activating kinase p42 | CDK20 | CDK20_HUMAN | Cell cycle-related kinase | Cell division protein kinase 20 | Cyclin-dependent kinase 20 | Cyclin-dependent protein kinase H | Cyclin-kinase-activating kinase p42
Type:
PROTEIN
Mol. Mass.:
38696.35
Organism:
Homo sapiens
Description:
ChEMBL_109746
Residue:
346
Sequence:
MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
  
Inhibitor
Name:
BDBM50519158
Synonyms:
CHEMBL4445812
Type:
Small organic molecule
Emp. Form.:
C21H13Cl2N3O2S
Mol. Mass.:
442.318
SMILES:
Clc1ccc(cc1Cl)C(=O)Nc1ccc2cc(ccc2c1)C(=O)Nc1nccs1
Structure:
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