Reaction Details Report a problem with these data
Target
Cathepsin L2
Ligand
BDBM50519377
Substrate
n/a
Meas. Tech.
ChEMBL_1875048 (CHEMBL4376337)
IC50
420±n/a nM
Citation
 Menezes, JCJMDS; Diederich, MF Natural dimers of coumarin, chalcones, and resveratrol and the link between structure and pharmacology. Eur J Med Chem 182:0 (2019) [PubMed]  Article 
Target
Name:
Cathepsin L2
Synonyms:
CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V
Type:
Enzyme
Mol. Mass.:
37341.06
Organism:
Homo sapiens (Human)
Description:
O60911
Residue:
334
Sequence:
MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
  
Inhibitor
Name:
BDBM50519377
Synonyms:
CHEMBL4438688
Type:
Small organic molecule
Emp. Form.:
C30H24O10
Mol. Mass.:
544.5056
SMILES:
O[C@H]1c2cc(O)c(O)cc2[C@H]([C@H](C(=O)c2ccc(O)cc2O)[C@@]1(O)C(=O)c1ccc(O)cc1)c1ccc(O)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: