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Target
Carbonic anhydrase 2
Ligand
BDBM50519436
Substrate
n/a
Meas. Tech.
ChEMBL_1875317 (CHEMBL4376606)
Ki
56300±n/a nM
Citation
 Tanini, D; Capperucci, A; Ferraroni, M; Carta, F; Angeli, A; Supuran, CT Direct and straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors. Eur J Med Chem 185:0 (2020) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50519436
Synonyms:
CHEMBL4472338
Type:
Small organic molecule
Emp. Form.:
C13H21NO2SSe
Mol. Mass.:
334.34
SMILES:
[#6]-[#6]-[#6@H](-[#6])-[#6@@H](-[#6][Se;v2])-[#7]S(=O)(=O)c1ccc(-[#6])cc1 |r|
Structure:
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