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Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50073723
Substrate
n/a
Meas. Tech.
ChEBML_40202
IC50
>10000±n/a nM
Citation
 de la Figuera, N; Martín-Martínez, M; Herranz, R; García-López, MT; Latorre, M; Cenarruzabeitia, E; del Río, J; González-Muñiz, R Highly constrained dipeptoid analogues containing a type II' beta-turn mimic as novel and selective CCK-A receptor ligands. Bioorg Med Chem Lett 9:43-8 (1999) [PubMed]  Article 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49196.59
Organism:
MOUSE
Description:
Cholecystokinin A CCKBR MOUSE::P56481
Residue:
453
Sequence:
MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANTWRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50073723
Synonyms:
(R)-3-[((2S,5S,11bR)-2-tert-Butoxycarbonylamino-3-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole-5-carbonyl)-amino]-4-phenyl-butyric acid | CHEMBL143012
Type:
Small organic molecule
Emp. Form.:
C30H34N4O6
Mol. Mass.:
546.6142
SMILES:
CC(C)(C)OC(=O)N[C@H]1C[C@H]2N([C@@H](Cc3c2[nH]c2ccccc32)C(=O)N[C@@H](CC(O)=O)Cc2ccccc2)C1=O
Structure:
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