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Target
Thromboxane A2 receptor
Ligand
BDBM50075089
Substrate
n/a
Meas. Tech.
ChEBML_225590
IC50
2.2±n/a nM
Citation
 Shinozaki, K; Sato, H; Iwakuma, T; Sato, R; Kurimoto, T; Yoshida, K Synthesis and thromboxane A2 antagonistic activity activity of indane derivatives. Bioorg Med Chem Lett 9:401-6 (1999) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36943.05
Organism:
RAT
Description:
Thromboxane A2 TBXA2R RAT::P34978
Residue:
341
Sequence:
MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
  
Inhibitor
Name:
BDBM50075089
Synonyms:
CHEMBL133420 | Sodium; [2-(4-chloro-benzenesulfonylamino)-indan-5-yl]-acetate
Type:
Small organic molecule
Emp. Form.:
C17H15ClNO4S
Mol. Mass.:
364.824
SMILES:
[O-]C(=O)Cc1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(Cl)cc1
Structure:
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