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Target
Thromboxane A2 receptor
Ligand
BDBM50075089
Substrate
n/a
Meas. Tech.
ChEBML_221825
IC50
360±n/a nM
Citation
 Shinozaki, K; Sato, H; Iwakuma, T; Sato, R; Kurimoto, T; Yoshida, K Synthesis and thromboxane A2 antagonistic activity activity of indane derivatives. Bioorg Med Chem Lett 9:401-6 (1999) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50075089
Synonyms:
CHEMBL133420 | Sodium; [2-(4-chloro-benzenesulfonylamino)-indan-5-yl]-acetate
Type:
Small organic molecule
Emp. Form.:
C17H15ClNO4S
Mol. Mass.:
364.824
SMILES:
[O-]C(=O)Cc1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(Cl)cc1
Structure:
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