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Target
B2 bradykinin receptor
Ligand
BDBM50403721
Substrate
n/a
Meas. Tech.
ChEBML_40107
Ki
11900±n/a nM
Citation
 Dziadulewicz, EK; Brown, MC; Dunstan, AR; Lee, W; Said, NB; Garratt, PJ The design of non-peptide human bradykinin B2 receptor antagonists employing the benzodiazepine peptidomimetic scaffold. Bioorg Med Chem Lett 9:463-8 (1999) [PubMed]  Article 
Target
Name:
B2 bradykinin receptor
Synonyms:
B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44467.17
Organism:
Homo sapiens (Human)
Description:
B2 BRADYKININ BDKRB2 HUMAN::P30411
Residue:
391
Sequence:
MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTLRTSISVERQIHKLQDWAGSRQ
  
Inhibitor
Name:
BDBM50403721
Synonyms:
CHEMBL2111994
Type:
Small organic molecule
Emp. Form.:
C30H27N5O
Mol. Mass.:
473.5683
SMILES:
[#7]\[#6](-[#7])=[#7]/c1cccc(-[#6]-[#7]-2-c3ccccc3-[#6](=[#7]-[#6@H](-[#6]-c3ccccc3)-[#6]-2=O)-c2ccccc2)c1 |r,c:18|
Structure:
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