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Target
N-formyl peptide receptor 2
Ligand
BDBM50520823
Substrate
n/a
Meas. Tech.
ChEMBL_1882214 (CHEMBL4383713)
IC50
3.2±n/a nM
Citation
 de Gaetano, M; Butler, E; Gahan, K; Zanetti, A; Marai, M; Chen, J; Cacace, A; Hams, E; Maingot, C; McLoughlin, A; Brennan, E; Leroy, X; Loscher, CE; Fallon, P; Perretti, M; Godson, C; Guiry, PJ Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A Eur J Med Chem 162:80-108 (2019) [PubMed]  Article 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM50520823
Synonyms:
CHEMBL4434857
Type:
Small organic molecule
Emp. Form.:
C26H37NO6
Mol. Mass.:
459.5751
SMILES:
CCCCC[C@H](O)c1nc(oc1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C)-c1ccccc1 |r|
Structure:
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