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Target
D(3) dopamine receptor
Ligand
BDBM50075365
Substrate
n/a
Meas. Tech.
ChEBML_58773
Ki
25±n/a nM
Citation
 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. Bioorg Med Chem Lett 9:585-8 (1999) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50075365
Synonyms:
2-[2-(4-Styryl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-1H-pyrrolo[2,3-b]pyridine | CHEMBL154482
Type:
Small organic molecule
Emp. Form.:
C22H23N3
Mol. Mass.:
329.4381
SMILES:
C(Cc1cc2cccnc2[nH]1)N1CCC(\C=C\c2ccccc2)=CC1 |c:25|
Structure:
Search PDB for entries with ligand similarity: