Reaction Details Report a problem with these data
Target
Retinoic acid receptor RXR-beta
Ligand
BDBM50075367
Substrate
n/a
Meas. Tech.
ChEBML_197079
Kd
15±n/a nM
Citation
 Vuligonda, V; Garst, ME; Chandraratna, RA Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands. Bioorg Med Chem Lett 9:589-94 (1999) [PubMed]  Article 
Target
Name:
Retinoic acid receptor RXR-beta
Synonyms:
NR2B2 | Nuclear receptor subfamily 2 group B member 2 | RXRB | RXRB_HUMAN | Retinoic acid receptor RXR-beta | Retinoid X receptor beta | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
56932.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_39045
Residue:
533
Sequence:
MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
  
Inhibitor
Name:
BDBM50075367
Synonyms:
(2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cyclohex-1-enyl)-vinyl]-furan-3-yl}-penta-2,4-dienoic acid | CHEMBL347411
Type:
Small organic molecule
Emp. Form.:
C21H26O3
Mol. Mass.:
326.4293
SMILES:
C\C(\C=C\c1ccoc1\C=C\C1=C(C)CCCC1(C)C)=C/C(O)=O |c:12|
Structure:
Search PDB for entries with ligand similarity: