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Target
Cellular retinoic acid-binding protein 2
Ligand
BDBM50265920
Substrate
n/a
Meas. Tech.
ChEMBL_1883815 (CHEMBL4385314)
Kd
160±n/a nM
Citation
 Tomlinson, CWE; Chisholm, DR; Valentine, R; Whiting, A; Pohl, E Novel Fluorescence Competition Assay for Retinoic Acid Binding Proteins. ACS Med Chem Lett 9:1297-1300 (2018) [PubMed]  Article 
Target
Name:
Cellular retinoic acid-binding protein 2
Synonyms:
CRABP-II | CRABP2 | Cellular retinoic acid-binding protein 2 | Cellular retinoic acid-binding protein II | RABP2_HUMAN
Type:
PROTEIN
Mol. Mass.:
15690.82
Organism:
Homo sapiens
Description:
ChEMBL_105504
Residue:
138
Sequence:
MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE
  
Inhibitor
Name:
BDBM50265920
Synonyms:
4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethynyl)benzoic acid | CHEMBL451835 | US9963439, BE23
Type:
Small organic molecule
Emp. Form.:
C23H24O2
Mol. Mass.:
332.4355
SMILES:
CC1(C)CCC(C)(C)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O
Structure:
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