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Target
Tyrosine-protein phosphatase non-receptor type 9
Ligand
BDBM50524069
Substrate
n/a
Meas. Tech.
ChEMBL_1891639 (CHEMBL4393466)
IC50
14000±n/a nM
Citation
 Liang, X; Zhang, X; Lu, X; Zheng, Z; Ma, X; Qi, S Diketopiperazine-Type Alkaloids from a Deep-Sea-Derived Aspergillus puniceus Fungus and Their Effects on Liver X Receptor ?. J Nat Prod 82:1558-1564 (2019) [PubMed]  Article 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 9
Synonyms:
3.1.3.48 | PTN9_HUMAN | PTP-MEG2 | PTPN9 | PTPase MEG2 | Protein-tyrosine phosphatase MEG2 | Protein-tyrosine phosphatase MEG2 (PTP-Meg2) | Tyrosine-protein phosphatase non-receptor type 9
Type:
n/a
Mol. Mass.:
68030.33
Organism:
Homo sapiens (Human)
Description:
P43378
Residue:
593
Sequence:
MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSSGQNLLAVESQ
  
Inhibitor
Name:
BDBM50524069
Synonyms:
CHEMBL4454177
Type:
Small organic molecule
Emp. Form.:
C23H25N3O4
Mol. Mass.:
407.4623
SMILES:
CC[C@@H](C)C1=C2N=C3OC=CC=C[C@]3(OC)C(=O)N2[C@@H](Cc2ccccc2)C(=O)N1 |r,c:4,9,11,t:6|
Structure:
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