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Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50524111
Substrate
n/a
Meas. Tech.
ChEMBL_1892113 (CHEMBL4394034)
Ki
4.0±n/a nM
Citation
 Hogendorf, AS; Hogendorf, A; Popio?ek-Barczyk, K; Ciechanowska, A; Mika, J; Sata?a, G; Walczak, M; Latacz, G; Handzlik, J; Kie?-Kononowicz, K; Ponimaskin, E; Schade, S; Zeug, A; Bijata, M; Kubicki, M; Kurczab, R; Lenda, T; Staro?, J; Bugno, R; Duszy?ska, B; Pilarski, B; Bojarski, AJ Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT Eur J Med Chem 170:261-275 (2019) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50524111
Synonyms:
CHEMBL4452569
Type:
Small organic molecule
Emp. Form.:
C13H11FIN3
Mol. Mass.:
355.1494
SMILES:
CCn1cncc1-c1c[nH]c2ccc(I)c(F)c12
Structure:
Search PDB for entries with ligand similarity: