Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50524440
Substrate
n/a
Meas. Tech.
ChEMBL_1893316 (CHEMBL4395237)
Ki
7.6±n/a nM
Citation
 Romeo, G; Prezzavento, O; Intagliata, S; Pittalà, V; Modica, MN; Marrazzo, A; Turnaturi, R; Parenti, C; Chiechio, S; Arena, E; Campisi, A; Sposito, G; Salerno, L Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands. Eur J Med Chem 174:226-235 (2019) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50524440
Synonyms:
CHEMBL4441396
Type:
Small organic molecule
Emp. Form.:
C17H23ClN2OS
Mol. Mass.:
338.895
SMILES:
Clc1ccc2sc(=O)n(CCCCN3CCCCCC3)c2c1
Structure:
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