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Target
Beta-lactamase
Ligand
BDBM50421413
Substrate
n/a
Meas. Tech.
ChEMBL_41360 (CHEMBL656039)
IC50
297±n/a nM
Citation
 Buynak, JD; Rao, AS; Doppalapudi, VR; Adam, G; Petersen, PJ; Nidamarthy, SD The synthesis and evaluation of 6-alkylidene-2'beta-substituted penam sulfones as beta-lactamase inhibitors. Bioorg Med Chem Lett 9:1997-2002 (1999) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
BLAC_STAAU | Beta-lactamase TEM | Penicillinase | blaZ
Type:
PROTEIN
Mol. Mass.:
31367.53
Organism:
Staphylococcus aureus
Description:
ChEMBL_41052
Residue:
281
Sequence:
MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALDTKSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
  
Inhibitor
Name:
BDBM50421413
Synonyms:
CL-307579 | TAZOBACTAM SODIUM | Tazocillin
Type:
Small organic molecule
Emp. Form.:
C10H11N4O5S
Mol. Mass.:
299.284
SMILES:
C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O |r|
Structure:
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