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Target
Toll-like receptor 2
Ligand
BDBM26194
Substrate
n/a
Meas. Tech.
ChEMBL_1896961 (CHEMBL4398996)
IC50
118110±n/a nM
Citation
 Bi, J; Wang, W; Du, J; Chen, K; Cheng, K Structure-activity relationship study and biological evaluation of SAC-Garlic acid conjugates as novel anti-inflammatory agents. Eur J Med Chem 179:233-245 (2019) [PubMed]  Article 
Target
Name:
Toll-like receptor 2
Synonyms:
CD_antigen=CD282 | TLR2_MOUSE | Tlr2 | Toll-like receptor 2
Type:
PROTEIN
Mol. Mass.:
89449.81
Organism:
Mus musculus
Description:
ChEMBL_117188
Residue:
784
Sequence:
MLRALWLFWILVAITVLFSKRCSAQESLSCDASGVCDGRSRSFTSIPSGLTAAMKSLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSLEHLDLSDNHLSSLSSSWFGPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDFAGLTSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLELRDTNLARFQFSPLPVDEVSSPMKKLAFRGSVLTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVTIRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQELYISRNKLKTLPDASLFPVLLVMKIRENAVSTFSKDQLGSFPKLETLEAGDNHFVCSCELLSFTMETPALAQILVDWPDSYLCDSPPRLHGHRLQDARPSVLECHQAALVSGVCCALLLLILLVGALCHHFHGLWYLRMMWAWLQAKRKPKKAPCRDVCYDAFVSYSEQDSHWVENLMVQQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILVLLEPIERKAIPQRFCKLRKIMNTKTYLEWPLDEGQQEVFWVNLRTAIKS
  
Inhibitor
Name:
BDBM26194
Synonyms:
4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | CHEMBL441343 | p-Hydroxybenzoic acid | phenol derivative, 8
Type:
Small organic molecule
Emp. Form.:
C7H6O3
Mol. Mass.:
138.1207
SMILES:
OC(=O)c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: