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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50082015
Substrate
n/a
Meas. Tech.
ChEMBL_105859 (CHEMBL717329)
EC50
42500±n/a nM
Citation
 Haskell-Luevano, C; Rosenquist, A; Souers, A; Khong, KC; Ellman, JA; Cone, RD Compounds that activate the mouse melanocortin-1 receptor identified by screening a small molecule library based upon the beta-turn. J Med Chem 42:4380-7 (1999) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r
Type:
PROTEIN
Mol. Mass.:
35238.60
Organism:
Mus musculus
Description:
ChEMBL_1498846
Residue:
315
Sequence:
MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIAITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDVLICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITYYKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAATLTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRSQELRMTLKEVLLCSW
  
Inhibitor
Name:
BDBM50082015
Synonyms:
(R)-9-(1H-Indol-3-ylmethyl)-5-naphthalen-2-ylmethyl-hexahydro-6-thia-3a,9-diaza-cyclopentacyclononene-4,10-dione | CHEMBL345096
Type:
Small organic molecule
Emp. Form.:
C29H29N3O2S
Mol. Mass.:
483.624
SMILES:
O=C1[C@H]2CCCN2C(=O)C(Cc2ccc3ccccc3c2)SCCN1Cc1c[nH]c2ccccc12
Structure:
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