Reaction Details Report a problem with these data
Target
Protease
Ligand
BDBM50526874
Substrate
n/a
Meas. Tech.
ChEMBL_1901569 (CHEMBL4403791)
IC50
6.3±n/a nM
Citation
 Ghosh, AK; Brindisi, M Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem 63:2751-2788 (2020) [PubMed]  Article 
Target
Name:
Protease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
10904.79
Organism:
Human immunodeficiency virus 1 (HIV-1)
Description:
Q9YQ12
Residue:
99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50526874
Synonyms:
NSC-670881 | SC-52151 | Telinavir
Type:
Small organic molecule
Emp. Form.:
C33H44N6O5
Mol. Mass.:
604.7397
SMILES:
CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1)C(=O)NC(C)(C)C
Structure:
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