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Target
Lactoylglutathione lyase
Ligand
BDBM50526947
Substrate
n/a
Meas. Tech.
ChEMBL_1901787 (CHEMBL4404009)
Ki
150±n/a nM
Citation
 Jin, T; Zhao, L; Wang, HP; Huang, ML; Yue, Y; Lu, C; Zheng, ZB Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Lactoylglutathione lyase
Synonyms:
4.4.1.5 | Aldoketomutase | Glo1 | Glx I | Glyoxalase I | Ketone-aldehyde mutase | LGUL_MOUSE | Lactoylglutathione lyase | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase
Type:
PROTEIN
Mol. Mass.:
20805.83
Organism:
Mus musculus
Description:
ChEMBL_10270
Residue:
184
Sequence:
MAEPQPASSGLTDETAFSCCSDPDPSTKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQKLDFPAMKFSLYFLAYEDKNDIPKDKSEKTAWTFSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKIATII
  
Inhibitor
Name:
BDBM50526947
Synonyms:
CHEMBL4584432
Type:
Small organic molecule
Emp. Form.:
C15H14O6
Mol. Mass.:
290.2681
SMILES:
Cc1cc(O)c(O)c(Oc2cc(C)c(C(O)=O)c(O)c2)c1
Structure:
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