Reaction Details Report a problem with these data
Target
Neutral alpha-glucosidase C
Ligand
BDBM50082234
Substrate
n/a
Meas. Tech.
ChEMBL_34411 (CHEMBL649415)
IC50
<50000±n/a nM
Citation
 Martin, OR; Compain, P; Kizu, H; Asano, N Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. Bioorg Med Chem Lett 9:3171-4 (1999) [PubMed]  Article 
Target
Name:
Neutral alpha-glucosidase C
Synonyms:
GANC_MOUSE | Ganc
Type:
PROTEIN
Mol. Mass.:
102002.29
Organism:
Mus musculus
Description:
ChEMBL_34410
Residue:
898
Sequence:
MEAAEKEEISVEDEAVDKTIFKDCGKIAFYRRQKQQLTKTTTYQALLGSVDTEQDSTRFQIISEATKIPLVAEVYGIEKDIFRLKINEETPLKPRLVCSGDTGSLILTNRKGDLKCHVSANPFKIDLLSKNEAVISINSLGQLYFEHLQVPHKQRATKGNGQNTPAATSQENQEDLGLWEEKFGKFVDVKANGPSSVGLDFSLHGFEHLYGIPQHAESHQLKNTRDGDAYRLYNLDVYGYQVHDKMGIYGSVPYLLAHKQGRTVGIFWLNASETLVEINTEPAVEYTLTQMGPAAAKPKVRCRTDVHWMSESGIIDVFLLTGPTPADVFKQYSYITGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKKRKLVVISDPHIKVDPDYTVYAQAKEQGFFVKNPEGGDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPELTMHKSAVHYGDWEHRELHNIYGFYQQMATAEGLIQRSKGKERPFVLSRSFFAGSQKYGAVWTGDNKAEWSYLKISIPMLLTLSVSGISFCGADVGGFIGNPEAELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEYTQLIREAIRQRYALLPYLYSLFYHTHVSSQPVMRPLWVEYPDDLETFAVEDEYMLGSALLVHPVTDPQTATIDVFLPGSDEVWYDSKTFAYWKGGCTVKIPVTLDTIPVFQRGGSVVPVKTTVGTSTGWMADSPYELRVALSTQGSAVGELYLDDGHSFQYLHQNQFLYRKFLFCSSVLTNRCANEKGHYPSKCIVEQILVLGLKKKPSSVTTHLSDGRAQPAAFTYCAETSALRLEKLSLRIGEDWEVRVG
  
Inhibitor
Name:
BDBM50082234
Synonyms:
(3R,4R,5S)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHEMBL320116
Type:
Small organic molecule
Emp. Form.:
C7H15NO5
Mol. Mass.:
193.1977
SMILES:
OCC1NC(CO)[C@H](O)[C@@H](O)[C@@H]1O
Structure:
Search PDB for entries with ligand similarity: