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Target
Free fatty acid receptor 3
Ligand
BDBM50527469
Substrate
n/a
Meas. Tech.
ChEMBL_1902642 (CHEMBL4404864)
EC50
537±n/a nM
Citation
 Ulven, ER; Quon, T; Sergeev, E; Barki, N; Brvar, M; Hudson, BD; Dutta, P; Hansen, AH; Bielefeldt, LØ; Tobin, AB; McKenzie, CJ; Milligan, G; Ulven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem 63:3577-3595 (2020) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 3
Synonyms:
FFAR3_HUMAN | FFAR3 | GPR41
Type:
PROTEIN
Mol. Mass.:
38655.15
Organism:
Human
Description:
ChEMBL_1508992
Residue:
346
Sequence:
MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
  
Inhibitor
Name:
BDBM50527469
Synonyms:
CHEMBL4448591
Type:
Small organic molecule
Emp. Form.:
C22H22N2O3
Mol. Mass.:
362.43
SMILES:
CC1=C(C(c2ccco2)C2=C(CCCC2=O)N1)C(=O)Nc1ccccc1C |t:1,10|
Structure:
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