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Target
Free fatty acid receptor 3
Ligand
BDBM50527464
Substrate
n/a
Meas. Tech.
ChEMBL_1902655 (CHEMBL4404877)
EC50
1318±n/a nM
Citation
 Ulven, ER; Quon, T; Sergeev, E; Barki, N; Brvar, M; Hudson, BD; Dutta, P; Hansen, AH; Bielefeldt, LŲ; Tobin, AB; McKenzie, CJ; Milligan, G; Ulven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem 63:3577-3595 (2020) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 3
Synonyms:
FFAR3_MOUSE | Ffar3 | Free fatty acid receptor 3 | G-protein coupled receptor 41 | Gm478 | Gm478 | Gpr41
Type:
PROTEIN
Mol. Mass.:
36514.65
Organism:
Mus musculus
Description:
ChEMBL_109430
Residue:
319
Sequence:
MGTSFFLGNYWLFFSVYLLVFLVGLPLNVMALVVFVGKLRRRPVAVDLLLLNLTISDLLLLLFLPFRMVEAACGMRWLLPFIFCPLSGFLFFTTIYLTSLFLTAVSIERFLSVAYPLWYKTRPRLAQAGLVSVVCWFLASAHCSVVYITEYWGNATYSQGTNGTCYLEFREDQLAILLPVRLEMAVVLFMVPLCITSYCYSRLVWILSRGASRRRRKRIMGLLAATLLIFFVCFGPYNMSHVVGYVSRESPSWRSYVLLLSTLNSCIDPLVFYFSSSKFQADFHQLLGRLLRTCVPWTQQVSLELKVKNGEEPSKECPS
  
Inhibitor
Name:
BDBM50527464
Synonyms:
CHEMBL4564389
Type:
Small organic molecule
Emp. Form.:
C21H18Cl2N2O3
Mol. Mass.:
417.285
SMILES:
CC1=C(C(c2ccco2)C2=C(CCCC2=O)N1)C(=O)Nc1cc(Cl)ccc1Cl |t:1,10|
Structure:
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