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Target
Mu-type opioid receptor
Ligand
BDBM50518026
Substrate
n/a
Meas. Tech.
ChEMBL_1906921 (CHEMBL4409279)
Ki
42±n/a nM
Citation
 Turnaturi, R; Chiechio, S; Salerno, L; Rescifina, A; Pittalą, V; Cantarella, G; Tomarchio, E; Parenti, C; Pasquinucci, L Progress in the development of more effective and safer analgesics for pain management. Eur J Med Chem 183:0 (2019) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50518026
Synonyms:
CHEMBL4449152
Type:
Small organic molecule
Emp. Form.:
C19H27N3OS
Mol. Mass.:
345.502
SMILES:
CC(Cc1ccsc1)NC(=O)NCC(Cc1ccccc1)N(C)C
Structure:
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