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Target
Chymotrypsin-like elastase family member 2A
Ligand
BDBM50085339
Substrate
n/a
Meas. Tech.
ChEBML_152309
IC50
130000±n/a nM
Citation
 Hayashi, Y; Iijima, K; Katada, J; Kiso, Y Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors. Bioorg Med Chem Lett 10:199-201 (2000) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Sus scrofa
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50085339
Synonyms:
((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid benzyl ester | CHEMBL303579 | acs.jmedchem.1c00409_ST.138
Type:
Small organic molecule
Emp. Form.:
C18H18ClNO3
Mol. Mass.:
331.793
SMILES:
ClCC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1
Structure:
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