Reaction Details Report a problem with these data
Target
Urease subunit alpha
Ligand
BDBM50532149
Substrate
n/a
Meas. Tech.
ChEMBL_1921927 (CHEMBL4424772)
IC50
71630±n/a nM
Citation
 Arshia, na; Begum, F; Almandil, NB; Lodhi, MA; Khan, KM; Hameed, A; Perveen, S Synthesis and urease inhibitory potential of benzophenone sulfonamide hybrid in vitro and in silico. Bioorg Med Chem 27:1009-1022 (2019) [PubMed]  Article 
Target
Name:
Urease subunit alpha
Synonyms:
3.5.1.5 | URE1_ECOLX | Urea amidohydrolase subunit alpha | ureC
Type:
PROTEIN
Mol. Mass.:
3418.90
Organism:
Escherichia coli
Description:
ChEMBL_106183
Residue:
30
Sequence:
MKTISRQAYADMFGPTTGDRLRLADTELFL
  
Inhibitor
Name:
BDBM50532149
Synonyms:
CHEMBL4443209
Type:
Small organic molecule
Emp. Form.:
C19H14Cl2N2O3S
Mol. Mass.:
421.297
SMILES:
[#8]-c1c(Cl)cc(Cl)cc1S(=O)(=O)[#7]\[#7]=[#6](\c1ccccc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: