Reaction Details Report a problem with these data
Target
Urease subunit alpha
Ligand
BDBM50532161
Substrate
n/a
Meas. Tech.
ChEMBL_1921927 (CHEMBL4424772)
IC50
68990±n/a nM
Citation
 Arshia, na; Begum, F; Almandil, NB; Lodhi, MA; Khan, KM; Hameed, A; Perveen, S Synthesis and urease inhibitory potential of benzophenone sulfonamide hybrid in vitro and in silico. Bioorg Med Chem 27:1009-1022 (2019) [PubMed]  Article 
Target
Name:
Urease subunit alpha
Synonyms:
3.5.1.5 | URE1_ECOLX | Urea amidohydrolase subunit alpha | ureC
Type:
PROTEIN
Mol. Mass.:
3418.90
Organism:
Escherichia coli
Description:
ChEMBL_106183
Residue:
30
Sequence:
MKTISRQAYADMFGPTTGDRLRLADTELFL
  
Inhibitor
Name:
BDBM50532161
Synonyms:
CHEMBL4536222
Type:
Small organic molecule
Emp. Form.:
C19H14N4O6S
Mol. Mass.:
426.403
SMILES:
[#8-]-[#7+](=O)-c1ccc(c(c1)-[#7+](-[#8-])=O)S(=O)(=O)[#7]\[#7]=[#6](\c1ccccc1)-c1ccccc1
Structure:
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