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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50088260
Substrate
n/a
Meas. Tech.
ChEMBL_90555 (CHEMBL699597)
IC50
420000±n/a nM
Citation
 Molteni, V; Rhodes, D; Rubins, K; Hansen, M; Bushman, FD; Siegel, JS A new class of HIV-1 integrase inhibitors: the 3,3,3', 3'-tetramethyl-1,1'-spirobi(indan)-5,5',6,6'-tetrol family. J Med Chem 43:2031-9 (2000) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50088260
Synonyms:
3,3,3',3'-tetramethyl-1,1'-spirobi(indan)-6,6'-dihydroxy-5,7'-bisurea | CHEMBL62411
Type:
Small organic molecule
Emp. Form.:
C23H28N4O4
Mol. Mass.:
424.4928
SMILES:
CC1(C)CC2(CC(C)(C)c3cc(NC(N)=O)c(O)cc23)c2c1ccc(O)c2NC(N)=O
Structure:
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