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Target
Galectin-1
Ligand
BDBM50077225
Substrate
n/a
Meas. Tech.
ChEMBL_1925953 (CHEMBL4429025)
Kd
24000±n/a nM
Citation
 Rajput, VK; MacKinnon, A; Mandal, S; Collins, P; Blanchard, H; Leffler, H; Sethi, T; Schambye, H; Mukhopadhyay, B; Nilsson, UJ A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model. J Med Chem 59:8141-7 (2016) [PubMed]  Article 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Beta-galactoside-binding lectin L-14-I | Gal-1 | Galaptin | Galectin-1 | LEG1_RAT | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Lgals1 | RL 14.5 | S-Lac lectin 1
Type:
PROTEIN
Mol. Mass.:
14853.16
Organism:
Rattus norvegicus
Description:
ChEMBL_118933
Residue:
135
Sequence:
MACGLVASNLNLKPGECLKVRGELAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWGTEQRETAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE
  
Inhibitor
Name:
BDBM50077225
Synonyms:
(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]thio}tetrahydro-2H-pyran-3,4,5-triol | CHEMBL52011 | THIODIGALACTOSIDE
Type:
Small organic molecule
Emp. Form.:
C12H22O10S
Mol. Mass.:
358.362
SMILES:
OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O |r|
Structure:
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