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Target
Adenosine kinase
Ligand
BDBM50533827
Substrate
n/a
Meas. Tech.
ChEMBL_1927381 (CHEMBL4430453)
Ki
9180±n/a nM
Citation
 Köse, M; Schiedel, AC; Bauer, AA; Poschenrieder, H; Burbiel, JC; Akkinepally, RR; Stachel, HD; Müller, CE Focused screening to identify new adenosine kinase inhibitors. Bioorg Med Chem 24:5127-5133 (2016) [PubMed]  Article 
Target
Name:
Adenosine kinase
Synonyms:
ADK | ADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
40545.97
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1467841
Residue:
362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
  
Inhibitor
Name:
BDBM50533827
Synonyms:
CHEMBL4457103
Type:
Small organic molecule
Emp. Form.:
C18H11N3O2
Mol. Mass.:
301.2988
SMILES:
O=C1NC(=O)c2c1nc(nc2-c1ccccc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: