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Target
Alpha-1B adrenergic receptor
Ligand
BDBM50090309
Substrate
n/a
Meas. Tech.
ChEBML_34344
Ki
680±n/a nM
Citation
 Patane, MA; DiPardo, RM; Newton, RC; Price, RP; Broten, TP; Chang, RS; Ransom, RW; Di Salvo, J; Nagarathnam, D; Forray, C; Gluchowski, C; Bock, MG Phenylacetamides as selective alpha-1A adrenergic receptor antagonists. Bioorg Med Chem Lett 10:1621-4 (2000) [PubMed]  Article 
Target
Name:
Alpha-1B adrenergic receptor
Synonyms:
ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor
Type:
Enzyme
Mol. Mass.:
56862.13
Organism:
Homo sapiens (Human)
Description:
P35368
Residue:
520
Sequence:
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
  
Inhibitor
Name:
BDBM50090309
Synonyms:
CHEMBL42514 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-yl)-propyl]-2-(3-fluoro-phenyl)-3-methyl-butyramide
Type:
Small organic molecule
Emp. Form.:
C27H34FN3O
Mol. Mass.:
435.5768
SMILES:
CC(C)C(C(=O)NCCCN1CCC(CC1)(C#N)c1ccccc1C)c1cccc(F)c1
Structure:
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