Reaction Details Report a problem with these data
Target
Proteasome subunit beta type-5
Ligand
BDBM50085536
Substrate
n/a
Meas. Tech.
ChEMBL_1930131 (CHEMBL4433382)
IC50
7100000±n/a nM
Citation
 Golonko, A; Pienkowski, T; Swislocka, R; Lazny, R; Roszko, M; Lewandowski, W Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system. Eur J Med Chem 167:291-311 (2019) [PubMed]  Article 
Target
Name:
Proteasome subunit beta type-5
Synonyms:
20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X
Type:
Protein
Mol. Mass.:
28480.96
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
263
Sequence:
MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
  
Inhibitor
Name:
BDBM50085536
Synonyms:
3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenzoic acid | CHEMBL288114 | Gallic Acid, F | gallic acid
Type:
Small organic molecule
Emp. Form.:
C7H6O5
Mol. Mass.:
170.1195
SMILES:
OC(=O)c1cc(O)c(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: